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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FOXO1
All Species:
17.88
Human Site:
T425
Identified Species:
39.33
UniProt:
Q12778
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12778
NP_002006.2
655
69662
T425
S
P
N
Y
Q
K
Y
T
Y
G
Q
S
S
M
S
Chimpanzee
Pan troglodytes
XP_522749
829
87557
T599
S
P
N
Y
Q
K
Y
T
Y
G
Q
S
S
M
S
Rhesus Macaque
Macaca mulatta
XP_001088437
860
91177
T630
S
P
N
Y
Q
K
Y
T
Y
G
Q
S
S
M
N
Dog
Lupus familis
XP_534487
524
56894
G296
N
Y
Q
K
Y
T
Y
G
Q
S
S
M
S
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1E0
652
69484
T422
S
P
N
Y
S
K
Y
T
Y
G
Q
S
S
M
S
Rat
Rattus norvegicus
XP_342245
649
69326
T419
S
P
N
Y
A
K
Y
T
Y
G
Q
S
S
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512968
514
54918
R286
S
S
P
S
P
D
Y
R
K
F
P
Y
G
Q
A
Chicken
Gallus gallus
Q90964
451
48838
S223
Y
W
M
L
D
P
S
S
D
D
V
F
I
G
G
Frog
Xenopus laevis
Q6EUW2
631
68449
G399
T
S
P
N
T
S
L
G
S
P
N
S
E
Y
R
Zebra Danio
Brachydanio rerio
NP_001070725
652
69329
G418
K
C
L
Y
G
Q
A
G
M
G
S
M
S
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95V55
613
67394
R385
C
S
C
M
H
N
A
R
D
G
L
S
P
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79
75.4
74.8
N.A.
92.6
92.2
N.A.
63.3
21.9
66.4
59.3
N.A.
29.7
N.A.
N.A.
N.A.
Protein Similarity:
100
79
75.6
77.2
N.A.
95.5
95.2
N.A.
69.9
35.4
76.7
72
N.A.
41.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
93.3
93.3
N.A.
13.3
0
6.6
20
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
20
6.6
13.3
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
19
0
0
0
0
0
0
0
10
% A
% Cys:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
19
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
28
0
64
0
0
10
10
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
0
10
0
46
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
10
0
0
0
10
0
0
0
10
% L
% Met:
0
0
10
10
0
0
0
0
10
0
0
19
0
46
10
% M
% Asn:
10
0
46
10
0
10
0
0
0
0
10
0
0
10
10
% N
% Pro:
0
46
19
0
10
10
0
0
0
10
10
0
10
19
0
% P
% Gln:
0
0
10
0
28
10
0
0
10
0
46
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
10
% R
% Ser:
55
28
0
10
10
10
10
10
10
10
19
64
64
0
46
% S
% Thr:
10
0
0
0
10
10
0
46
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
55
10
0
64
0
46
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _